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In an ever changing RWD Landscape. You need a RWE SherpaTM to guide you.


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def. in mountaineering the term has become synonymous for expert guides that carry heavy supplies and support across treacherous & difficult terrain.

Through our the intuitive RWE SherpaTM platform, Navidence provides RWE Researchers with the tools to take the guesswork out of defining an RWE study’s data needs.

RWE SherpaTM  allows RWE Researcher to navigate and qualify RWD sources & solutions, match them directly to study requirements and stakeholder expectations, and support collaboration across your organisation as you establish the overall strategy for use of RWD. 

RWE SherpaTM brings consistency to the development of Fit-4-Purpose Real World Data strategy, and enhances trust in the use of Real World Data for your RWE study via curation of a library of Computable Operational Definitions (CODef) to drive both a clear understanding of the data needs for each study purpose as well as the necessary data queries.

We are consistently adding to our CODef libraries all the time.

Scroll through our current indication specific CODef Libraries that are immediately available in RWE SherpaTM


General and Indications A-H


General: Basic Study Elements


General: Co-Morbidities




Bladder Cancer (Non-Muscle Invasive)


Chronic Kidney Disease/End Stage Renal Disease


Colorectal Cancer




CV Outcomes

Indications H-Z

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Design with Confidence

RWE Study Design and RWD Assessment are commonly performed in silo’s due to the time and resource constraints. RWE Study Design elements are typically firstly aligned with scientific literature, and then subsequent RWD assessment is performed to determine the viability of obtaining effective data and generate evidence from a given dataset. This can give rise to rework of study designs based on the results of RWD assessment.


Navidence offers a platform not only for creation of Computable Operational Definitions (CODefs) to allow a tech-optimized approach to RWD Assessment, but also for the collection and creation of a library of results on those RWD sources assessed against those CODef enchanced criteria. This allows RWE teams to design with confidence, utilizing those study design elements that are likely to be available in the final data assets you wish to utilise for your project.

Improve Knowledge Management

By using the Navidence platform to create and curate a library of Computable Operational Definitions (CODefs), as well as results of RWD assessments, RWE Teams can enhance collaboration by creating a central source of RWE Design knowledge.

RWE Teams can continually enhance and enrich the collective knowledge of Operational and Data definitions in each area of research, transform them into computable format to empower RWE Design and RWD Assessment, and distribute this knowledge swiftly and seamlessly across your organisation.

Consistent RWE Design

By utilizing CODefs within your RWE SherpaTM library, you can ensure that you have consistent robust scientific justifications for each Conceptual and Operational Definition (CODef) used within your study protocol when submitting to regulators. RWE Researchers can also ensure the consistent application of these across all studies within your field of RWE Research.

Consistent RWD Assessment

By utilizing CODefs within your RWE SherpaTM library, you can ensure that you can provide queries to your data partners that are aligned with the data, ensuring your partners feel they are always fairly assessed against study requirements.

Enhancing transparency and consistency in your Real World Data partnerships can significantly improve speed and accuracy of RWD Assessment overall.

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Discuss how RWE SherpaTM can support you with one of our experts.


If you would like to hear more about how SherpaTM can support RWE Design and RWD Assessment in the Age of Data, we'd love to hear from you!